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In its comment to CMS, Biogen questioned the agency's legal grounds for limiting coverage of aducanumab. Limiting Medicare coverage of aducanumab for treatment of AD means "the progression of disease, for nearly all beneficiaries, would continue unabated," Biogen wrote in its comment to CMS last week. CMS should "fully consider the broad ramifications and significant unintended consequences of prematurely placing unduly severe restrictions on the entire class of anti-